The largest randomised study to investigate the treatment and prevention of recurrent venous thromboembolism (VTE) has recruited the first of its 7500 patients, researchers announced last week during the 54th Congress for Thrombosis and Haemostasis (Nuremberg, Germany)…

Patients with inflammatory bowel diseases (IBDs) such as Crohn’s disease or ulcerative colitis do perceive a benefit from thiopurine treatment. A report in the open access journal BMC Gastroenterology has demonstrated improved health-related quality of life in 92 IBD patients…

A low-carbohydrate diet, a low-fat diet and the Mediterranean diet were equally effective in helping obese people to reverse carotid atherosclerosis after losing moderate amounts of weight and improving their blood pressure, in a study reported in Circulation: Journal of the American Heart Association…

Researchers at Albany Medical College are releasing results of a study this week that they say will help refocus the search for new drug targets aimed at preventing or reversing the devastating tissue inflammation that results after heart attack and stroke. In the March 5 issue of the Journal of Biological Chemistry, lead author Alejandro [...]

Previous research has found that activation of the anterior cingulate cortex (ACC) is associated with risk factors for alcohol use disorders - such as low alcohol effects and positive alcohol expectations - among adolescents…

Each year, two in every 100,000 young athletes succumb to sudden cardiac death, fueling a debate over what constitutes a comprehensive health screening prior to sports participation…

New research has identified four aspects of immune system disturbance which lead to the development of coeliac disease. Nearly 40 different inherited risk factors which predispose to the disease have now been identified…

Alcohol dependence (AD) is a complex disease for which both genetic and environmental factors affect susceptibility. Previous research had identified several genes associated with AD through linkage analysis or candidate-gene approaches. Findings from a genome-wide association study (GWAS) support an association between AD and a cluster of genes on chromosome 11…

Oxygen for ethanol oxidation is supplied through breathing, the stomach, and the skin. There is a great deal of genetic and environmental variability in the pharmacokinetics of alcohol absorption, distribution, metabolism, and elimination. A new study has found that increasing dissolved oxygen concentrations in alcohol may help to reduce alcohol-related side effects and accidents…

Alcohol use disorders (AUDs) are influenced by multiple genetic, environmental and behavioral factors, which makes it difficult to find individual genetic markers to help identify those at risk of developing AUDs. This study examined how a person’s level of response (LR) to alcohol, which is closely linked to the development of AUDs, is related to [...]